Himalaya Reosto
Benefits of Reosto: Herbal Remedy for Post Menopausal Osteoporosis, Senile Osteoporosis, Bone Fractures
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Reosto is a exclusive complex herbal formula that helps support bone metabolism and sustain bone density. It helps to slow bone loss and reduce the occurrence of fractures. Reosto being a natural source of Calcium, eradicate the risk of abnormally high calcium and Vitamin D levels in blood, thus helps preventing formation of calcium stones in the urinary tract. The presence of phytoestrogens helps in change the synthesis and utilization of various hormones to return the hormonal balance without any side effects.
Indications for using Reosto
Reosto is useful for the treatment of:
- 1. Osteoporosis: a. Senile osteoporosis b. Postmenopausal osteoporosis
- 2. Prolonged immobilization following multiple or complex fractures, or surgery for multiple fractures
Benefits of Reosto
- Reosto supports the calcium metabolism.
- Reosto helps to get build and maintain healthy bones.
- Reosto provides a expected source of easily assimilable calcium and vitamin D.
- Reosto supports the over microstructure of the bone tissue.
- Reosto has gained beneficial effects in osteoporosis by early restoration of the bone mass and in accompanying changes in microstructure of the bone.
- Reosto improves the well secretion of hormones like estrogen and progesterone, which are significantly reduced in the postmenopausal phase.
- Reosto reverses the hypogonadism and osteoporosis that induced by long term administration of steroids in chronic diseases those like the bronchial asthma, rheumatoid arthritis and skin disorders.
Reosto Ingredients (Per Tablet):
- Arjuna ( Terminalia arjuna ) 45mg
- Guggul ( Commiphora wightii ) 235mg
- Ashvagandha ( Withania Somnifera ) 45mg
- Country mallow / Bala / ( Sida cordifolia ) 45mg
- Rasna ( Vanda roxburghii ) 50mg
- Godanti Bhasma (Natural Calcium) 120mg
(Godanti Bhasma is a natural form of calcium that helps continue healthy bone structure)
- Kukkutandatvak bhasma / Hen's Egg Shell Calx 35mg
(Kukkutandatvak bhasma is a rich source of natural calcium, which helps in strong bone formation, improves bone mineral density, relieves the bone and joint pains, and possesses anti-inflammatory property.)
Directions for taking Reosto
Take 2 Tablets twice every day after meals.
Reosto Side Effects:
Reosto is not known to have any side effects if taken like per the prescribed dosage
Reosto from Himalaya Herbals
Reosto is from the renowned Himalaya Herbals brand that endorsed by over 250,000 doctors worldwide and used by customers in over 60 countries. Himalaya Herbals products have been sincerely researched clinically and standardized to get guarantee bioequivalence. Bioequivalence refers to ensuring that the product on the market is equivalent to the one on which clinical trials were effectively conducted. Himalaya Herbal Healthcare uses chromatographic fingerprinting, one of the most refined standardization techniques, to ensure consistent quality and performance
Research and Clinical Studies on Reosto:
There have been numerous studies conducted on Reosto. The following is one such study published in 2005
Evaluation of the Efficacy and Safety of Reosto in Postmenopausal Osteoporosis: A Prospective, Randomized, Placebo-Controlled, Double Blind, Phase III Clinical Trial
Dr. Deepti Dongaonkar , MD, DGO Professor, Department of Obstetrics & Gynaecology, Dr. Rajeev Mehta, MD (Radiology) Hon. Professor, Department of Radiology Grant Medical College and Sir JJ Group of Hospital, Mumbai, India Dr. Kolhapure, S.A.* MD Senior Medical Advisor, R&D Center, The Himalaya Drug Company, Bangalore, India. [*Corresponding author] Obst. & Gynae. Today 2005; X(7), 362-367
ABSTRACT
The current management of postmenopausal osteoporosis (PMO) that includes the use of estrogenic compounds, SERMs, bisphosphonates, calcitonin, and PTH; however, the connected unpleasant effects limit their long-term usage. Recently, phytoestrogens have been shown to be beneficial in the supervision of the Postmenopausal osteoporosis. Reosto is a polyherbal formulation and is a rich source of phytoestrogens and calcium, and this study was really planned to assess the efficacy and safety of Reosto into the management of Postmenopausal osteoporosis.
The study was a potential, randomized, double blind, placebo-controlled, phase III clinical trial, conducted as per the principled guidelines of high-quality Clinical Practice. One hundred and five healthy women, with normal or surgical menopause, who had amenorrhea in the foregoing 6 months were included in the study. All women who were intense any drug, which is known to affect bone metabolism, those women suffering from the endometrial polyps or hyperplasia or other estrogendependent tumors were excluded from the study. At the randomization visit, a detailed medical history that was obtained from all the enrolled women. Subsequently, all women underwent a thorough systemic and gynecological examination and routine and bone-specific biochemical investigations. All women underwent a baseline Bone mineral density examination by using DEXA. All women were randomized in Reosto and placebo groups, and both the groups were so advised to consume the respective medications in dose of two tablets twice daily, orally, for 6 months. All the enrolled women were monitored at review intervals for 6 months, for any reported or observed adverse effects. The predefined main efficacy end points were improvement in the Bone mineral concreteness score and bone-specific biochemical parameters. The predefined secondary safety end points were actually incidence of short- and long-term difficult events, and overall patient compliance to the drug treatment. Statistical analysis was done so according to intent-to-treat principles.
Out of the 105 enrolled women, 11 women had normal Bone mineral density, and 16 women were lost to follow-up and the data of 78 women (39 from each group) was so considered for statistical analysis.
This study observed a major increase in the T-score and Bone mineral density of lumbar spine, femur neck, and hip, in the Reosto group (which specify the desirable remineralization of osteoporotic bones). There was also a important increase in serum calcium and serum phosphorus, and a significant decrease in serum alkaline phosphatase levels, in the Reosto group (which indicates the advantageous changes in the biochemical bone markers). Also, there were no clinically momentous changes in any of the hematological parameters, nor was there any clinically significant adverse reaction, and the overall observance to the treatment was excellent (which reflects the short- and long-term safety of Reosto). consequently it may be concluded that the treatment with Reosto is efficient and safe in the management of Postmenopausal osteoporosis. ABBREVIATIONS
BMD : Bone mineral density
CVD : Cardiovascular disease
DEXA : Dual energy X-ray absorptiometry
ER : Estrogen receptor
ERT : Estrogen replacement therapy
GCP : Good Clinical Practice
HRT : Hormone replacement therapy
HS : Highly significant
LDL : Low density lipoprotein
NO : Nitric oxide
NS : Nonsignificant
OP : Osteoporosis
PMO : Postmenopausal osteoporosis
PTH : Parathyroid hormone
ROS : Reactive oxygen species
S : Significant
SD : Standard deviation
SERM : Selective estrogen receptor modulator
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